Abstract Objective: To analyze the difference of PlGF and TNF-α serum level between early-onset and late-onset preeclampsia.Method: This is a cross-sectional analytic comparative study comparing serum level of PlGF and TNF-α between groups with earlyand late-onset preeclampsia. Each group consists of 32 subjects who met inclusion criteria and presented to Dr. Hasan Sadikin Hospital orits …
Over expression and premature activation of matrix metalloproteinase (MMP) can lead to degradation of amnion chorionic membrane which clinically called premature rupture of membrane (PROM). Increasing MMP activity caused by matrix metalloproteinase-9 (MMP-9) gene polymorphism (C-1562T) will be followed by apoptosis. This study was aimed to find the differences between MMP-9 expression and cerv…