process Dengue shock syndrome (DSS) is the most severe from of dengue hemorrhagic fever (DHF) and has a high mortality. There are two major pathological changes in DHF determine the severity of sisease, plasma leakage and bleeding. Cytokines release during the immune responase in dengue virus have been throught to be mediators of the. The study involed 50 children with DSS of whom 13 (26%) died…