Abstract: Cubebin is a lignan isolated from Indonesian plant Piper cubeba L.f fruits. Cubebin has been found to strongly inhibit contraction of isolated-trachea of guinea pig induced by histamine or metachoJine. In the present study, the effect of cubebin was investigated on histamine release from rat peritoneal mast cells (RPMCs), a connective tissue mast cell. Compound 48/80 (G Protein activa…
Kayu angin is a liken that grows in Indonesia forests and commonly used to cure diarhea, stomachache, and cough. Based on the densitometric method, yellow kayu angin (KAK) contained 4.09 percent (from the dry weight) of major substance (substance A), and 2.99 percent of major substance (substance B) from green kayu angin (KAH). Previously, these substances were identified as uric acid which inh…
A toxicity test was performed on separately 11 extracts of Indonesian medicinal plant (Elaeocarpus gramiflorus J.E. Smith, Vitex negundo L., Leucaena leucocephala (Lmk) de Witt, Borreria articularis (L.f) F.N. Will, Ardissia humilis vahl., Achyranthus bidentata L., Hyptis capitata Jack., Gynura procumbens (Lour.) Merr., Annona squamosa L., Annona murricata L. and Artemisia vulgaris L.,) by 'Bri…