Diltiazem HCI is used as an antihypertensiON and has a very short half-Iife, making ii suitable if made in the form of microcapsules. Research using HPMC and Eudragit RS 30 D as coating end aimed at finding the best ratio of diltiazem HCI microcapsules prepared by spray drying method, in terms of the dissoluiion profile. The microcapsules are made in a homogeneous solution of the active substan…
A test of cytotoxic activity of pentacyclic triterpenes 12,13-Dihydro-1-α- amirin-20-30-en-3-acetate and 12,13-Dyhydro-α-amirin-20-30-en-30l compounds on, myeloma cells and their docking has been conducted. Two compounds were treated on myeloma cell which their cells densities have been determined. They were subssequently incubated with a series of compound dosage from 2000 µg/ml to 125 µg/…
Life expectancy in Indonesia was increasing every year as impact of access to health services. On 2004, number of elderly people is 16.5 million, 52.6% is female. The most health problem facing by female elderly was osteoporosis that it proved by incidence of oesteoporosis among female was higher thatn male. Infact of that one out of three female tends to have osteoporosis: meanwhile the incide…
A research about anti-bacterial activity and components of esssential oil from leaves and peels of Citrus amblycarpa have been done. The components of essential oil had been identified by using GC-MS and anti-bacterial activity against S. Aureus ATCC 25923 and E. Coli ATCC 25922 had been determined with liquid dilution method. The component of essential oil from leaves that can be identified ar…
Finding new substances from natural resources is quite important, especially those possessing medical usage. This experiment was perfomed in order to isolate and elucidate the stucture of pentacyclic triterpene and sterol substances from Eupatorium in lifolium H.B.K. leaves. The structural elucidation of those substances was performed using IR, UV, mass spectrometer 1H and 13C NMR. The result s…