ABSTRACT: Introductions: Thalassaemia is a most prevent of monogenk hematological diseases in the world& population. Carrier detection is a very important step for thalossemia prevention pro¬gram. Recently Banyumas has many thalassaeinia patients. howaver not supported by the accu¬rate data about thalassaemia carrier in the general population. Purpose: ldentifring thefrequency of thalassesni…