Tetrahydropentagamavunon-O (THPGV-O) is assumed to be main metabolite product of biotransformation process of PGV-O. THPGV-O was synthesized by converting PGV-O to the compound by hydrogenation with PdjC as a catalyst. PGV-O potently inhibited the histamine release from ~at mast cells in vitro and in vivo, however, ironically only traces amount of compound was found in the blood. THPGV-O is ass…
Abstract: Isolation and identification of secondary metabolites from root of Jatropha gossypifolia, and also its biological activity test toward microbes and turnor cells have been conducted. isolation was carried out by using vacuum Iiqiud chromatography (VLC) method (adsorbent: silica gel, eluent: mixture of n-hexane, ethyl acetate, chloroform, and methanol). The isolate molecular structure w…
Seventeen traditional medicinal plants of South East Sulawesi are collected at Arboretum Prof. Mahmud Hamundu Universitas Haluoleo have been determined by Herbarium Bogoriense staff, Cibinong Bogor. The plants came from Konawe and Konawe Selatan districts. Endemicity of those plants were based on ethnobotanial study using information from “Tokoh Masyarakat Tolaki” and “Tokoh Masyarakat Ja…