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Kurang energi protein (KEP) merupakan salah satu bentuk malnutrisi karena rendahnya asupan gizi. Pada KEP gambaran histopatologi liver akan menunjukkan perlemakan hati yang bereaksi dengan radikal peroksidasi membentuk lipid peroksidasi yang meningkatkan ekspresi Interleukin6 (IL-6). Penelitian ini dilakukan untuk membuktikan bahwa konsumsi serbuk daun kelor dapat menur…
The increase in the population of older persons needs to be accompanied by increased quality of healthcare in older persons, particularly a decrease in the incidence of infections. Impaired immune responses are common in older adults,and immune senescence likely contributes to the increased incidence of infectious diseases in the older persons. The aging process decreases the immune response a…
The use of drugs that inhibit the renin-angiotensin system is one of the effective way to intervene in the pathogenesis of cardiovascular and renal disorders, especially in hypertension treatment. The idea of blocking the renin system at its origin by renin inhibitor has existed for more than 30 years. Renin inhibitor supresses the covension of angiotensinogen into angiotensin, and further deac…
Background: Over the last 10 years, we have investigated thalassemia patients in Jakarta to obtain a comprehensive picture of iron overload, oxidative stress, and cell damage. Methods: In blood samples from 15 transfusion-dependent patients (group T), 5 non-transfused patients (group N) and 10 controls (group C), plasma lipids and lipoproteins, lipid-soluble vitamin E, malondialdehyde (MDA) …
Formulation of Dipyridamole Sustained Relese Tablet Using Floating System. Dipyridamole is a drug for prevention of postoperative thromboembolic of heart valve replacement and long term therapy of angina pectories will he well absorhed in stomach. To maintain therapeutic plasma concentration in long time and to increase biovalability is needed a sustained release dosage form having the long res…
The fragile X syndrome is the most common form of inherited mental retardation in humans, caused by an expansion of the cytosine-guanine-guanine (CGG) repeat in the fragile X mental retardation 1 (FMR1) gene located on the X chromosome. Antibody tests have been developed to identify fragile X patients, based on the presence or absence of fragile mental retardation protein (FMRP) in both lymphoc…
Current management of schizophrenia emphasizes on eclectic approach using bio-psychosocial theories. In conjunction with the standard anti-psychotic terapy, the eclectic counseling is thought to enhance clinical outcomes of patients with schizophrenia, by accelerating adaptive capacity recovery that allows normal function of the patients in the society. This study aimed to determine the effect…
Sodiumascobyl phosphate is a hydrophilic derivate of asorbic acid, which has chemically more stable. As an antioxidant it can scavengeand destory aggressive oxidizing agents and free radicals that are improtantly involved in the skin aging process. Microemulsion is carrier systems for topical delivery of sodium ascophate. An experiment has been conducted with virgin coconut oil (VCO) as an oil …