This research was conducted to know the influence of Justicia gendarussa Burm. F leaves water extract as hypouricemic agent in white rats male (rattus novergicus) strain Sprague-Dawley that has been pretreated with potassium oonate. Thirty five rats were devided randomly into 7 groups. Oral administration of all test drugs was given for 8 days. There were 3 group doses variations of J. gendarus…