Background: Osteoarthritis is a joint disease most often found in the community. Patients with osteoarthritis are frequently drink non steroidal anti inflammatory drugs such diclofenac sodium. Data has shown too many side effects of diclofenac sodium especially to the kidney function. A research data in Malang shows that people who use herbs were 476 persons in city area and 580 persons in dist…
Background: The prevalence of osteoarthritis (OA) in the community is high and this disease is the second largest cause of physical disability in the world. Degeneration and joint inflammation occurred in OA. Curcuminoid is a secondary metabolite present in the rhyzome of turmeric and ginger. Curcuminoid could be used to treat rheumatic diseases. Diclofenac sodium is able to inhibite the produc…
In osteoartritis there are degeneration process and joint inflammation. Curcuminoid is a secondary metabolite found in Curcuma domestica that can be used to treat rheumatic disease. The aim of this study is to know the effect of curcuminoid from Curcuma domestica Val. extract to the level of malondialdehyde (MDA) in the synovial fiuid of osteoarthritic joint, Diclofenac sodium was used as comp…
Calprotectin, a major cytosolic of lekocytes, is detected in neutrophils and monocytes/machrophages. This protein is known to be a marker for several inflamatory disease including periodontitis. In type 2 diabetea mellitus patients, the severity of periodontitis strongly thought caused decreasing of leukocytes fanction such as neutrophluls. Previous research found that the calprotectin level in…
Characteristic of mucosal immunity is the production of secretory IgA (SIgA) by local plasma cells at the mucosal tissues and secretory glands. The IgA secretion into luminal side is a complex process, involving various steps of molecular and cellular interactions among the immunocompetent cells. These comprise (1) initiation of mucosal responses in the gut lymphoid tissues (gut-associated lymp…
Characteristic of mucosal immunity is the production of secretory IgA (SIgA) by local plasma cells at the mucosal tissues and secretory glands. The IgA secretion into luminal side is a complex process, involving various steps of molecular and cellular interactions among the immunocompetent cells. These comprise (1) initiation of mucosal responses in the gut lymphoid tissues (gut-associated lymp…
Food allergy is an immediate type of hypersensitivity reactions against food allergens. The sensitization by those allergic substances will induce the IgE antibody production by B lymphocytes in the systemic circulation and the gut mucosa. Increased mecosal permeability facilitates this process of sensitization. Conversely, there is a protective effect of SIgA antibodies against the uptake of m…