The main compound of Uncaria gambir Roxb. (gambir), catechin and it’s derivates have been believed to be potential as antiviral. Epigallocatechin gallate (EGCG) and epicatechin are catechin derivates which are found to be potential as antiviral against Human Immunodeficiency Virus (HIV). However, gambir extract also contains quercetin that has possibility to be mutagenic. Therefore, a pre…
Understanding interaction between viruses and host cells during infection process is the first step in discovering appropriate drugs and vaccines against viral diseases. Advance technologies based on genomics and proteomics approaches provide great tools to disclose the complexity of virus-host interaction. In this essay, the application of RNAi screens method and proteomics-based approaches on…
Abstrak Munculnya penya kit degeneratif pada orang dewasa bisa berhubungan dengan fase perkembangan sewaktu di dalam rahim. Asupan nutrisi selama tahap perkembangan ini dapat mempengaruhi gen yang meregulasi epigenetik. Telah banyak penelitian yang menemukan bahwa asupan nutrisi selama kehamilan akan mempengaruhi status kesehatan anak yang akan dilahirkan. Akan tetapi, baru sedikit yang meneli…
Selective serotonin re-uptake inhibitors (SSRIs) have been considered to be promising drugs in psychiatric practice because of their selectivity to serotonin re-uptake transporter (SERT). Sertraline and fluoxetine are considered to be effective SSRIs as their ability in binding SERT and inhibit neurotransmitter recycling. However, they also bind norepinephrine and dopamine transporter (NAT and …