ABSTRACT Traditionals drugs is used one of alternative for treatment kidney stone. One of them by utilizing grape blue (Vitis vinifera L.). This research aimed to know influence ethanol and cloro form fraction addition grape blue to kidney stone calcium solubility, It was analized with Spektrofotometer Serapan Atom (SSA) methocie by in vitro. 100 mg pollen kidney stone steeped in 10 mL ethanol…