Daun dewa (Gynura pseudo-china Aug DC), empirically used as anti-inflammatin, antidiare, anti-tumor, and anti-fungus additionally, it also used to prevent blood vessel contriction, and stimulate the immune system. The leaf from Daun Dewa empirically used to dengue fever treatment. In this study, 25 while rats Wistar strain were used which is divided into 5 groups: 1) control group, 2) study gro…