The antiacne activity of paste and powder of chitosan – Garcinia mangostana extract nanoparticles were observed that it’s against of Propionibacterium acnes. The paste of nanoparticles has been prepared by ionic gelation reaction by mixture 0.2% chitosan solution in acetic acid with Garcinia mangostana 70% ethanol extract and it’s continued by reaction process with 0.1% sodium tripolyphos…