ABSTRACT: BACKGROUND Cervical cancer ranks second among female cancers worldwide and is widely associated with human papilloma vtrus (HPV) infection. However, HPV infection progression is influenced by various host factors. Epidermal growth factor (EGF) is a host factor important for proper epithelial proliferation and development, and may play a ro…
INTRODUCTION Cervical cancer cases are ris ing and many women are infected with human papillomavirus (HPV). Interferon gamma (IFN-a) is one of the key regulatory cytokines that influence the HPV clearance. The production and the function of 1 FN-a may impaired by the defect of the IFNG gene leading to the cervical malignant progression. This study aimed to examine the association between IF.I…
Background: Natural resistance associated macrophage protein (NRAMP) is a proton/ divalent cation transporter which play a roll in iron trafficking in the phagosomes. Variations in NRAMP1 gene have been reported to be associated with susceptibility to tuberculosis (TB) because Mycobacterium tuberculosis (MTb), the causative agent of TB, compete with its host to uptake iron for its metabolism. T…
Indonesia is fifth in the tuberculosis (TB) prevalence globally and this country is one of the largest tobacco producers. Smoking has been reported to be an important risk factor for TB and a reduction in smoking could be expected to have a significant impact on TB incidence and prevalence. However, studies from various countries yielded conflicting results. Our study aims to explore the associ…