LR-2 is a compound analog of monastrol, an anticancer agent, which has been succesfully synthesised through the application of Biginelli reaction and one of LR compound series that synthesised in faculty of Farmacy, Universitas Gadjah Mada. This research was aimed to synthesized the LR-2 compound and to investigate the cytotoxicity of LR-2 on breast cncer cell line. The reaction was carried out…