ABSTRACT Etidronic acid is used as an antioxidant in skin care products. Etidronic acid was commonly identified by Gas Chromatography/Mass Spectroscopy. The main purpose of this research is to analyze and identify of etidronic acid in cosmetics by high performance liquid chromatography (HPLC). In this study (HPLC analysis) is using UV-Vis detector, column C18 (250 x 4.6 mm), mobile phase A [ac…
Curcumin in Curcuma xanthoryza could inhibit cytochrom P-450 CYP1 A 1, CYP1 A2 and CYP4A. It has been used as herbal remedy safely as anti inflammation. The aim of the research at find the effects of the herbal on AUC and Cmax ibuprofen ofmale rats. Male rats ofWistar strain with bodyweight between 180-200g was used as test animals. Test animals in the control group was given ibuprofen suspensi…
Amphetamine-type stimulant (ATS) is a group of substances that have similar properties like amphetamines. The ATS get serious attention, because it stimulates the Central Nervous Sysytem (CNS) as phamacological properties. The ATS in it’s misuse in young generation. This study aims to find out the ATS in urine samples and other content and it’s comperative result of ATS analysis by using r…
Testosterone undecarnoate was one of the esters of testoterone. Microemulsion was selected as the formula for testoterone undecanote based on the clinical considerations and their physico-chemical properties. This study aims at finding catch optimum conditions for the analysis of testosterone undercanoate in microemulsion by high performance Liquid Chromatography (HPLC) and a vaidation is also …
Using of multiple drug therapy could cause interaction. Based on the study of Curcuma xanthoryza,which it contains curcumin that it could inhibit cytochrom P-450 CYP1A 1, CYP1A2 and CYP4A It is used as herbal medicine which is safe to be used for anti inflammation. This research is aimed at finding the effect of the herbal on AUC and Cmax ibuprofen on male mice, where the both compound are meta…
Multiple myeloma (MM) is a neoplasm of mature and immature plasma cells. The clinical manifestation of this disorder results from the uncontrolled and progressive proliferattion of these cells, the effect of marrow replacement, and the over production of M-component. The incidence is varies and rise with age. In the last five years, in Hasan Sadikin Hospital-Bandung, we found thirty seven cases…
Myelotoxicity secondary to treatment of malignancies with chemotherapy/radiation therapy gives rise to infection which can be fatal. GM-CSF is a hemopoeitic growth factor that regulates growth and function of granulocytes (neutrophyl and eosinophyl), and monocytes/macrophages. Four hundred u micrograms of GM-CSF (leucomax) is given subcutaneously in five consecutive days to eight cases of acute…
A multicenter, clinical trial, randomized open label and parallel study has been done since April 1993 on the Chronic Myelogenous Leukemia patients treated with either Interferon (I) + Hydroxyurea (HU) or Interferon + low dose Ara-C (C). The countries who involve on this study are Indonesia, China, India, Philippines, Singapore, South Korea and Taiwan. The dose of Interferon is 5 MU 5 days a we…