Over expression and premature activation of matrix metalloproteinase (MMP) can lead to degradation of amnion chorionic membrane which clinically called premature rupture of membrane (PROM). Increasing MMP activity caused by matrix metalloproteinase-9 (MMP-9) gene polymorphism (C-1562T) will be followed by apoptosis. This study was aimed to find the differences between MMP-9 expression and cerv…
The incidence ofpreeclampsia in Indonesia (1980-2001) was around 6-8% of the total pregnancies with maternal mortality rate 9.8-25%. In preeclampsia, an increase of apoptosis occurs as a result of a decrease ofBc1-2 expression before a pregnancy reached full term. The objectives of this study were to determine placental apoptosis index (AI) in preeclampsia and normal pregnancy, and its correlat…
Prediction and early detection of preclampsia is very important to reduce maternal and maternal and perinatal morbidity and mortality. This researchwas to find out the difference of serum sFIf1 level between normal pregnancy and severe preeclampsia (SPE) and to determine the corelation of serum sFIt1 level with blood pressure as well as the degree of potentenuria. This was an analytic observati…