LR-2 is a compound analog of monastrol, an anticancer agent, which has been succesfully synthesised through the application of Biginelli reaction and one of LR compound series that synthesised in faculty of Farmacy, Universitas Gadjah Mada. This research was aimed to synthesized the LR-2 compound and to investigate the cytotoxicity of LR-2 on breast cncer cell line. The reaction was carried out…
Sarang semut (Myrmecodia pendans) is an Indonesian native plant that has been used in folk medicine. Researches showed sarang semut has antioxidant effect, xantinoxidase inhibitor potency, and anticancer activity. The efficacy and safety of this plant should have been proven before used in modern medicine. The objective of this research was to assess the potency of acute toxicity, evaluate tox…
Beban cedera makin meningkat sehingga dibutuhkan penyediaan dan penyajian data yang cepat dan terbaru. Sistem dokumentasi data cedera dari berbagai sumber masih bersifat manual sehingga pemanfaatan data kurang optimal. Diperlukan model sistem registri data dasar trauma yang sederhana, aplikatif, informatif dan mudah diakses oleh pengguna sebagai penunjang sistem surveilans cedera. Penelitian in…
hypercholesterolemia. Worse. Stichopus hermanii extract is a source of saturated fatty acid containing omega 3 which can decresaes triglyceride blood level. The aim of this research was to investigate the efffect of Stichopus hermanii extract in triglyceriblood level of wistar rats which got periodontitis. The sample of this research were 30 rats dividedinto 5 groups namely group K(-) as negati…
hypokalemia, defined as a plasma potassium concentration
Steroid resistant nephrotic syndrome (SRNS) due to nephrotic syndrome type 2 (NPHS2) gene mutation has more severe clinical manifestation than those without mutation. This study was designed to find NPHS2 gene mutation in 412C→T and 419delG in Indonesian SRNS and to see differences in clinical manifestation. The observational cross sectional study was performed on 88 SRNS. Subjects were taken…
The increasing in the life span of patients with major thalassemia should be followed by increased quality of life. There are factors which can affect growth retardation in these patients. The aim of this study was to find out the risk factors for growth retardation in patients with major thalassemia. An analytical study with cross-sectional design was conducted at Pediatric Thalassemia Clinics…
Valid and reliable information on causes of deaths in the community is important to provide basic data and information for health policy formulation and program development, set health priorities, evaluate program effectiveness and for research. In order to evaluate the completeness of vital registration, the mortality registration system data would be assessed through a dual record system. The…
Death reporting is base of mortality rate calculation. The mortality rate is importance indicator and should be decreased in the well-being develop plan. To find a good death reporting, local goverment in Indonesia were developing registration systems for some region in Indonesia. Surakarta City and Pekalongan District have been developing registration with repairing cause of death report, this…
Despite the tremendous overall improvement on maternal mortality and infant mortality still there is significant public health issue, commands and enormous amount of attention of these subjects in Indonesia. One of the main issues is how to provide high-quality services to the community in order toreduce maternal mortality and infant mortality including neonatal mortality. This article is to an…