The aim of the present study was at preparing and evaluating different formulation of ketokonazole in microemulsion base by using virgine conconate oil (VCO) as oil phase. Tween 80 used sufactant and sorbitol as-sufactant. Five different formulations were formulated with values of oil (5%) and surfactant (35%, 40%, 50%, 55%)and co-surfactant (10%). Mocroemulsion of ketoconazole also made but wi…
This study was done in order to collect the corresponding data about the complex interaction between the drug and the mixed additive, consisted of surfactant like agent andnonionic surfactant, and the membrane modification. The in vivo investigation of the acetosal suspension contained poliethylene glycol (PEG) 400 and tween 80 (PT) 1 percent, 3 percent, and 10 percent have been carried out. Th…