Fllngsi utama n//lieus at/a/ab fIIcncipftlleLln kestabilan, me'!iaga PH netral dan sebagai sawar terhadap pepsin, sebingga mclindungi tIIukosa dari clI,{jlJl proteo/itik pencernaan. Sedangkan flmgsi taama sekresi bikarbonat adalab menetraiean asas: yang berdifilSi ke datam IIl11kllS dan IIItmelibam pH yang mendeeati netral-netrai antara nlllkus - 11Iukosa. Pada kondisi fisiolog;s fllngsi sasuar…
Ulcer healing process is an intricate and active process including reconstruction process of mucosa through formation of granulation tissue. Granulation tissue formation takes place by means of formation of ulcer base, formation of blood vessel (angiogenesis) and re-establishment of glandular architecture. The process of granulation tissue formation on the ulcer base takes place 48-72 hours aft…
Peptic mucus synthesize especially prostaglandine E2 and I2. Prostaglandine E2 and I2 can impede acid secete and stimulate mucus and bicarbonate secretion. Misoprostol, a synthetic methyl ester analogue of prostaglandin is both a powerful inhibitor of gastric secretion and is able to protect the gastroduodenal mucosa from damage. Misoprostol and other prostaglandine derivatives can be alternati…
Helicobacter pylori is a gram negative bacteria with spiral S, curved shaped that lives only in microaerophilic condition. This bacteria lives between and underneath the mucous of human gastric mucous. A lot of studies in the world showed that H. pylori has a dominan role in peptic ulcer disease and chronic active gastritis. H. pylori strain which has Cag A, 128 kDa surface protein and positive…
Stress ulcer is defined as an acute mucosal lesion of the upper gastrointestinal tract caused by an indirect influence of several pathological situations such as brain tumor, severe burn, patients with multiorgan failure and stroke. Many investigators have reported the prevalence of stress ulcer among patients with stroke. This article will report the result of endoscopic examination among pati…