Candida sp are the most common fungal pathogens causing fatal health care associated infections. Among the genus of Candida, Candida albicans is the most frequent species isolated from patients. The notorious C. albicans infection is the ability of th is dimorphic fungus to form biofilm. Biofilm has been pointed as a dynamic phenotypic switching in bacteria and fungi, which may result in higher…
Oleandrin in one of cardenolida compound isolated from and active fraction of Nerium indicum Mill leaves. (fam. Apocynaseae), which have cytotxic effect on several human cancer cells, and also to normal cells in vitro. Another compound which was potential as renal anticancer has also been isolated from N. indicum. However, its chemical structure has not been discovered. The aim of this study wa…
The flowers of kamilen (Matricaria chamomilla, L) has been used as antifungal in Indonesian traditional medicines. Previous study showed that the extract of flowers inhibited Candida albicans activity. In order to determine the active fraction, the bioactive-guided fractionation method was used. The air-dried flowers was extracted from methanol. Methanolic extracts was fractionated by using n-…