Previous study described that ethanol 7% extract of Acelypha indica have immunomodulator effect baseon increasing of phagocyte activity, not only in vitro but also by in vivo studied. In this study, immunomodulator activity was tested using five group of mice. Each group was given standard diet, negative group was given 0,5% NaCMC suspensitive group was given Stimuno 0,39 mg/20g BW, 3rd, 4th, …