ABSTRACT One side effect of non-steroidal anti-inflammatory drugs is gastric mucosal irritation, possibly causing gastric ulcers. The aim of this study was to evaluate the protective effect of cincau leaves ( Cyclea barbata Miers) on aspirin-induced gastric ulcer in Balb/c mice. Twenty five Balb/c mice (20-30 g, 2-3 months old)were randomly divided into 5 groups. Group I-III were given cincau…
ten generates clinical symptoms such as gastritis or peptic ulcer. Bee honey has high nutrient has been shown to have a protective effect against drugs destroying stomach. The purpose of this study was the difference effect of honey in various concentrations on the gastrohistopathological image in male white Wistar rat induced with indomethacin. Design and Methods: This was an experimental rese…
Gastrointestinal toxicity due to non-steroid anti-inflamatory drugs can be inhibited by the compounds that have antioxidant activity. Quercetin is a flavonoid that has antioxidant activity and protection effect against ulcer. Chlorination of quercetin anhanced the antioxidant. This study aims to obatin the chlorinated derivative of quercetin and examine the protection effect against acetosal-i…