Plectanthus Scutellaroides (L) R.Br., or jawer kotok, Family Lamiaceae, growts widely in Indonesia, and has a long history of therapeutic usage in Indonesia traditional jamu to cure various diseases. The brownish purple leaves of Plecranthus contain alkaloids, saponin, flavonoids, tannin, volatile oils, and quercetin which has been proven to exert antiinflammatory activity. In this research whi…
Gastrointestinal toxicity due to non-steroid anti-inflamatory drugs can be inhibited by the compounds that have antioxidant activity. Quercetin is a flavonoid that has antioxidant activity and protection effect against ulcer. Chlorination of quercetin anhanced the antioxidant. This study aims to obatin the chlorinated derivative of quercetin and examine the protection effect against acetosal-i…
Quercetin is a flavonoid having anti-inflammatory activity by cyclooxygenase -2 inhibition. In addition quercetin has a cytoprotective activity against gastric ulcer due to its antioxidative activity. The objevtive of this research was to obtain quercetin derivative through selective acetylation and to find out the anti-inflammatory activity and gastric ulcer side effect of the synthesis produc…