Psoriasis vulgaris is a chronic inflammatory skin disease characterized by variable features. The exact cause of psoriasis is still unknown but numerous studies have identified tumor necrosis factor-α (TNFα) as a cytokine regulating inflammatory cascade. TNF-α and its receptors (sTNFRI & sTNFRII) plays important roles in the induction of psoriatic lesions. Topical corticosteroid remain one o…