Background: The goal of this study was to analyze the correlation of oxidative stress in human glioma cells with tumor grade in order to explore the role of oxidative stress as a marker in determining the tumor progression. Methods: Samples were 21 brain tumors and 5 normal brain tissues from glioma patients. Oxidative stress was analyzed by measuring malondialdehyde (MDA), carbonyl and 8-hyd…
Aim This study analyze the MnSOD gene expression as endogenous antioxidant in human glioma cells compared with leucocyte cells as control. Methods MnSOD gene expression of20 glioma patients was analyzed by measuring the relative expression ofmRNA and enzyme activity of MnSOD in brain and leucocyte cells. The relative expression of mRNA MnSOD was deter¬mined by using quantitative Real Time RT-…