Abstract Plants, Has Long Been Known To Be One Of The Most Important Resource In Treatment Efforts And The Efforts To Maintain Public Health. Papain Is The Dried Powder Derived From The Sap Of The Leaves, Stems, Roots And Fruits Of Papaya (Carica Papaya L), Which Can Treat Skin Keratoderm. In This Study Gelformulations With Active Ingredient Papain Concentration Of 5%, Karbopol 940 As A Gellin…