Abstract Objective: To find out whether diabetes mellitus and/or hypertension is associated with endometrial cancer and could increase the staging of the cancer.Method: This was an analytic retrospective descriptive study with cross sectional design. Data were taken from the medical record of patients diagnosed as having endometrial cancer in Obstetrics and Gynecology Department of Dr. Hasan Sa…
Anemia merupakan faktor prognostik independen untuk pertahanan hidup pasien kanker. Penurunan kapasitas oksigen pada darah dapat menyebabkan terjadinya kondisi hipoksia pada jaringan kanker . Hipoksia pada jaringan kanker dapat mengaktivasi faktor transkripsi hypoxia-inducible factor-1α (HIF-1α) yang kemudian akan mentranskripsi banyak gen lain yang terlibat dalam invasi sel, angiogenesis, me…
Endometrial cancer is one of the most invasive gynaecological malignanccies. Hormonal imblance has several causes, one of which is the excessive estrogen exposure. The imbalance has been linked to the development of endometrial hyperplasia, which is the largest member of the tyrosine kinases receptor. Activation of EphB4 receptor by ephrin-B2 ligans is through to play an important role in the e…
Endometrial cancer can strike all ages, especially more than 50 years of age, the higher the age the higher the woman's endometrial cancer risk occurs. Approximately 75% of endometrial cancers occur in over 50 years of age. Preliminary Study Results at clinik out patient Gynecology Oncology at Dr. Soetomo Hospital in April 2010, from 10 patients with endometrial cancer, as many as eight people …