Oxidative stress has been implicated in pathogenesis of diabetes mellitus. In addition to increased production of free radicals, antioxidant defense systems are disturbed in diabetes mellitus. As a result, oxidative stress may cause oxidative damage of B-cell pancreas. Hydnophytum formicarum consists of flavonoid which function as an antioxidant. So that, it necessary do research to know influe…
Aim This study aimed to elicit the protective effect of Sargassum echinocarpum extract on endothelial dysfunction in thoracic aorta of streptozotocin-induced diabetic rats. Methods The animals were divided into 5 groups. The first was normal, the second was diabetic non treated animals. The third to fifth groups were the diabetic animals which given Sorgassum echinocarpum extract (150; 300, an…