The most common carcinoma of the uterine cervix is squamous cell carcinoma (75%). Numerous studies have emphasized the importance of cyclooxygenase-2 (COX-2) activity during carcinogenesis and overexpressed in any kind of malignancies. The purpose of this study was to investigate the expression of protein COX-2 and its correlation with the differentiation grading in squamous cell carcinoma…
Adenoid cystic carcinoma (ACC) is the most common salivary gland malignancies, with high rate of local recurrence and unpredictable prognosis. Based on previous research, prognosis of ACC in salivary gland which is correlated with survival rates, is related with histopathological malignancy degree based on its growth pattern type. This study was conducted in Pathology Anatomy Department of Medi…
Different from developed countries, molecular characteristic of colorectal adenocarcinoma (CRC) among Indonesians in the age group of ≤40 years old is mostly similar compared to the CRC of the age group of >40 years old, and both are sporadic cancers. To know the association of molecular characteristic with the risk factors of CRC, a cross sectional study was conducted to analyze the associat…
Background: This study aims to analyze whether the expressions of E-cadherin and NM23HI can be used as predictors of ductal carcinoma metastasis in various degrees of malignancies. Methods: Paraffin blocks were obtained from 97 patients with invasive breast ductal carcinoma with malignancy grade 1, 2 and 3 who came to several hospitals in Jakarta and Bandung from 2000 to 2006. Histopatholog…
Public warning from BPOM RI 2009 indicated that some equipment plastic cup, plastic electrical kettle and melamine plate was not eligible. To understanding acute toxicity that equipment, we done acute toxicity test of water soaked within plastic cup, plastic electrical kettle, and melamine plate to Hap G2 cell and lympocyte cell. These experiments aimed at getting LD50/IC50 that toxicity of wa…
Endometrial cancer is one of the most invasive gynaecological malignanccies. Hormonal imblance has several causes, one of which is the excessive estrogen exposure. The imbalance has been linked to the development of endometrial hyperplasia, which is the largest member of the tyrosine kinases receptor. Activation of EphB4 receptor by ephrin-B2 ligans is through to play an important role in the e…
To evaluation the role of prostate basal cell staining in diagnosing Gleason score 6 prostate cancer. During research period, we collceted 20 medical records and paraffin block specimens of Gleason score 6 prostatic adenocarcinoma patients. Specimens were taken from prstate needle biopsy.Demographic data and PSA level were extracted from medical records. Basal cells were detected by immunohisto…