This research is conducted to analyze the effcet of ethanol extract of daruju root (A. Illiofollus L) on the mice hepatocyte which is inducted by carbon tetrachloride. Ethanol extract of daruju root is fed to the mice (per oral) with 250 mg/kg, 1000 mg/kg, and 4000 mg/kg weight dosage in 7 days. On day 8, the mice sample is given by carbon tetrachloride which is dissolved in olive oil. As negat…
Ferro sulphate (FeSO.) overload and carbon tetrachloride (Gel.) are chemical hepatacarcinogen. Ferro sulphate disrupts the redox balance of the cell and generates chronic oxidative stress by which modulates signaling networks related to malignant transformation. Meanwhile ecl. induces hepatic damage in lipid peroxidation and decreases activities of antioxidant enzymes and generation of free rad…