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ABSTRACT Thyroid hormone is essential for maintaining structure and function of the heart. In normal condition, thyroid hormone preserves the strength of heart contraction (inotropy) to meet physiological demand.Thyroid diseases, either hyperthyroidism or hypothyroidism, cause pathologic heart abnormalities called thyroid heart diseases. The patologic heart abnormalities due to thyroid hormo…
ABSTRACT In day-to-day clinical setting, physician frequently deal with the uncertainty in clinical decision making. Conceptual framework is needed to make valid and satisfying clinical as well as ethico-legal decision. Six steps in conceptual framework for ethical reasoning: (1) state the problem plainly (2) gather and organize data (3) is the problem ethical? (4) is more information or dia…
ABSTRACT Dyspareunia (painful sexual intercourse) is a recurrent or persistent acute pain associated with attempted or complete vaginal entry and/or penile vaginal intercourse. Prevalence in the community is between 0,4-61%. In general gynecological practice, the prevalence is up to 15%.The objective ofthis review isto provide a review of literature and to review current data or issue regard…
ABSTRACT: Although infrequent, cervical cancer is the most commonly diagnosed malignancy during pregnancy. The overall incidence of cervical cancer in pregnancy ranging from 7.5 to 45.0 cervical cancers per 100,000 pregnancies. The aim of this review was to provide information about the difficulties in diagnosing and managing cervical cancer during pregnancy. A systematic review of the liter…
ABSTRACT Thyroid disease is common in reproductive age including in pregnancy. Abnormal thyroid hormone level, either too low or too high, can lead to bad outcomes in pregnancy. Hypothyroidism must be corrected, considerably before the pregnancy, with supplementation and also high intake of rich-iodine foods as it is the most common cause of neurologic deficit. Hyperthyroidism in pregnancy c…
ABSTRACT Antiphospholipid syndrome (APS) is defined as an autoimmune disorder characterized by recurrent thrombosis or obstetrical morbidity. One of obstetric complications in patients with APS is HELLP syndrome (occurring in 0.01 to 0.2% of pregnancies). One to 5% of healthy individuals have antiphospholipid antibodies (aPL). Clinical manifestations of APS are recurrent venous or arterial t…
ABSTRACT Imminent abortion is when a woman might be losing her baby during the first half of pregnancy; is the commonest complication in pregnancy and is a serious emotional burden for women. It has increased risk of miscarriage, preterm delivery, low birthweight, perinatal death, antepartum haemorrhage and premature rupture of the membrane, however the risk of a malformed surviving infant d…
ABSTRACT Pain due to endometriosis is still an important problem in female reproductive health. However the exact mechanism as well as the pathognomonic pain type in endometriosis is still enigmatic. There were evidences,that estrogen, inflammatory process, and the presence of nerve fibers near endometriotic lesion may contribute to this problem. Understanding the interaction between those f…
ABSTRACT Breast cancer is the most frequent cancer and cause of cancer death in women, and is also the most common cancer in pregnant and lactating women, occurs in 1 of every 3,000 pregnancies, Breast changes during pregnancy make clinical assessment difficult. Cancers are usually detected at later stage. Ultrasound and a mammogram can be performed with little risk to the fetus. Biopsy is i…
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a progressive, degenerative motor neuron disease. Understanding of etiopathogenesis and biomarker is the best ways towards ALS management. The recent finding of biomarker ALS offers hope to ALS sufferers. A comprehensive aspects of ALS have been discussed, including, history, epidemiology, etiopathogenesis, clinical pictures, diagnostic criteri…