Antibiotic problem is a part of drug problem in general and involves all over the world with different extent. Where as antibiotic development does not necessarily produce a real breakthrough drug. Fluoroquinolone is one of succesefull discovery which worth discussing. Meanwhile, drug resistence incessantly takes place as to require rational drug prescribing practices. The prescribed drug shoul…
We reviewed all typhoid fever patients hospitalized in our department from January 1, 1990 until December 31, 1994. From 645 patients of typhoid fever diagnosed clinically, only 131 patients (20.3 percent) were confirmed bacteriologically, and 61 patients (9.5 percent) had sensitivity test result. The patient's age ranged from 2-13 years, 71 (54.2 percent) of them were females. From 131 patient…
We reported the bacterial suscetibility pattern of 4.365 laboratory isolates during 1995. Fifty six species of bacteria were indentified, consisted of 11 gram positive spesies from 2002 isolates, and 45 gram negative species from 2,363 isolates. More than one fifth (22.96 percent) of the isolates, and 45 gram negative species from 2,363 isolates. More than one fifth (22.6 percent) of the isolat…
The outcome of antibiotic administration to overcome a particular infection depends on three interactive factors i.e., the drug, the patient and the causative pathogen(s). From the drug point of view there are two important factors i.e, the antimicrobial potency and the pharmacokinetic profile of the antibiotic being used. To obtain a satisfactory result, it is desired that the antimicrobial co…
Corneal ulcers is one of the difficult case to handle, most of them causes a blindness. It needs an antibiogram in order to choose drug of choice, however, it takes time. So sensitivity patterns is important as guidance to choose an initial antibiotic treatment to the patient. Sensitivity test of 42 isolates from 33 corneal ulcer patients against 12 antibiotics have been done, using disc diffus…