Hypoxia exposed trophoblast cells will cause apoptotic process, that correlate with up-regulation of p53 and Bax protein expression; and down-regulation of anti-apoptotic Bcl-2; also find both on trophoblastic sample from preeclampsial eclampsia complicated pregnancy, and normal pregnancy. The aim of this study is, to prove that the amount of apoptotic trophoblast cells on trophoblast tissue sa…
Diabetes mellitus may induce types of deleterious impacts. The maternal deleterious impacts include the increasing tendency for pre eklamsi incidents as much as four times. The URJ Hamil I RSU Dr. Soetomo Surabaya in 2005 has recirded 0,5% of diabetes mellitus incidents which have led to pre eklamsi. Although the percentage is uite small, the complications which accurred during pregnancy, deli…
Preeclampsia is a disease in pregnancy and carcterized by hypertension and proteinuria. Preeclampsia and eclampsia are the must causes of maternal and fetal mortality and morbidity in Indonesia. Placental and systemic oxidative stress caused endothelial cell dysfunction and injury. Placental oxidative stress also linked to fetal growth restriction. HSP70 is essential for cellular recovery, surv…
Hypoxia exposed trophoblast cells will cause apoptotic process, that correlate with up-regulation of p53 and Bax protein expression; and down-regulation of anti-apoptotic Bcl-2; also find both on trophoblastic sample from preeclampsial eclampsia complicated pregnancy, and normal pregnancy. The aim of this study is, to prove that the amount of apoptotic trophoblast cells on trophoblast tissue sa…
HELLP (hemolysis, elevated liver enzymes and and low platelets) syndrome is multisystem diseases from of preeclampsia/eclampsia marked by microangiopathic hemolytic anemia, heapetic dysfunction and thrombocytopenia. The teminology and diagnostic criteria used to describe this syndrome have been confusing and inconsistent. The etiology of the HELLP syndrome in preeclampsia is poorly understood, …
Anesthesia in preeclampsia-eclampsia allows enesthesiologists to modify their routine anesthetic practice to preeclampsia-eclampsia allows enesthesiologists to modify their routine anesthetic practice to provide optimum care for these high-risk parturients. The anesthesiologists must understand the pathophysiology of preeclampsia-eclampsia. He must be flexible plan ahead and communicate activel…
Objective : To study the lipid plasma profile of preeclampsia and normotensive pregnancy as an additional information in explaining the pathogenesis of preeclampsia. Design/data identification : Clinical, analitycal, cross sectional and prospective study. Setting : 1) Department of Obstetrics and Gynecology Dr. Soetomo Hospital/Medical School, Airlangga University, for taking the venous blood s…