Piroksikam is non streoid anti inflammation drug (NSAID) with small dose (10-20 mg daily) with a long time (t1/2) elimination. Piroxicam formulation was expected able to yield a good (quality) tablet to physical characteristic standard. Tablet r component was consisted of Flowlac 100 (filler), Avicel PH-101 (binder) and compritol 888 ATQ (lubricant). The research was done with simplex lattice …
Using the wet granulation method, the granules are prepared by adding the granulating liquid to the powder mass and mixed throughly. A rough way of determining the end point during the granulation process is to press a portion of mass in the palm of the hand. Three binders are starch, gelatin and Carboxy Methyl Cellulose (CMC) had been studied as wetting granulation liquid. The end point of gra…
The possibility of using a conventional coating-pan by modifying its interior part to prepare film coated tablet has been studied. The aim of the study is to use the conventional coating pan for preparing film coated tablet faster. Pharmacoat-606 was used as film coating after being solubilized in ethanol. Film coating was done by spreading the pharmacoat-606 solution using both conventional an…
Using the wet granulation method, the granules are prepared by adding the granulating liquid to the powder mass and mixed throughly. A rough way of determining the end point during the granulation process is to press a portion of mass in the palm of the hand. Three binders are starch, gelatin and Carboxy Methyl Cellulose (CMC) had been studied as wetting granulation liquid. The end point of gra…