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In view of demographic trends, andrology will increasingly be concerned with problems of the aging male, especially with aspects of fertility. While there is considerable interindividual variation, fertility in men usually persists well into old age. However, increased occurence of spontaneous mutations means a higher genetic risk for children of older fathers. Diminished androgen levels in old…
Even though many efforts have been done for fifteen years since the birth of the world's first test tube baby, the rate of assisted reproductive delivery was still low. Nowadays, tubal replacement procedure becomes more popular than the uterine transfer. However, this technique still ends up with a very high incidence of abortion. Many workers claimed that coculture system resulted in more prom…
Lysozyme has an ability to degrade some substrates of carbohydrate derivative, lipid and protein, it might also capable to degrade membrane cell of bacteria as well as antibiotics. Therefore the influence of lysozyme toward antibiotic activity had been investigated. The experiments performed using 7-Amino Cephalosporanic Acid (7-ACA) group, (sephalexin and sephradin) and 6-Amino Penicillanic Ac…
The aim of this research is to obtaine a sustained release dosage form with cellulose derivatives by microencapsulation method. In this study, the microencapsulation method modified from Lordi, by spraying the ethanolic solution of methylcellulose, ethylcellulose and hydroxyprapyl methylcellulose. Particles of the active substance were put in the coating pan and sprayed carefully with the solut…
Anthistamines such as CTM, diphenhydramine HCI, promethazine HCI and astemizol have different physicochemical properties due to the differences in their chemical structures. These physicochemical properties would affect their transport behavior through cellophane membrane. This study would like to investigate the effect of physicochemical properties of the antihistamines on their transport thro…
The effectiveness of sun screen depends on the stability of drug used as an active compound, and its influence on the chemical components in skin cell. To study of the effectiveness of octylmethoxycinamate (OMC) as sun screen, the phostostability of OMC was examined by exposing the compound with direct sunlight. The influence of OMC on the stability of tryptophan was also studied. The layer was…
The objective of this study is to ascertain the effects of Testosterone enanthate (TE) or 19 - Nortestosterone hexyloxy phenyl - propionate (19-NT) plus Depot medroxyprogesterone acetate (DMPA) on the semen production in healthy Indonesian men. The prospective study consisted of 2 phases i.e a control phase and treatment phase. Forty normal healthy male volunteers received seven weekly injectio…