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Takayasu arteritis is a chronic, inflammatory large vessel arteriopathy that primarily affects the aorta, is main branches, and the pulmonary arteries. Fibrosis and thickening of the arterial wall often occur in later stages, resulting in a cerebrovascular accident. A 20-year old man presented with ischemic stroke of young adults due to Takayasu’s arteritis, from which he had been suffering …
A key issue of Really Significant Genes (RSG) that caused Graves Disease in unresolved. RSGs are considered likely major contributors to genetic risk for a disease. These genes should be strongly linked within families and they could become clinically useful as predictor of disease. Some Graves Disease susceptibility genes have been identified. The first identified was the Human-Leucocyte-Antig…
Faraogenomi bertujuan untuk mengoptiasi strategi pengobatan dengan memperhatikan factor genetic dan epigenetic pasien. Hipermetilasi promoter adalah proses epigenetic yang menghambat eksprei gen. Hipermetilasi gen MGMT terjadi di sekitar 30-40% pasien glioblastoma. Tindakan bedah yang dikuti dengan kombinasi oabt Temozolomide (obat sitotoksik yng meng-alkilasi DNA) dan terapi radiasi merupakan …
Myasthenia gravis (MG) is an acquired autoimmune disorder characterized dinically by weakness of skeletal muscles and fatigability on exercise. Weakness increases during the day and improves with rest. Extraocular muscle (EOM) weakness or ptosis is present initially in 50% of patients and 90% accurs during the course of illness. AChE inhibitors and imunomodulating therapies are the mainstays of…