LR-2 is a compound analog of monastrol, an anticancer agent, which has been succesfully synthesised through the application of Biginelli reaction and one of LR compound series that synthesised in faculty of Farmacy, Universitas Gadjah Mada. This research was aimed to synthesized the LR-2 compound and to investigate the cytotoxicity of LR-2 on breast cncer cell line. The reaction was carried out…
.5 per 1 juta anak, tertinggi adalah leukemia, kemudian kanker mata/retinnoblastoma, kanker tulang. CNS, dan linfoma. Dengan pengembangan model registrasi kanker di DKI Jakarta, mekanisme kerja registrasi kanker sudah disepakati, diperoleh insidens kanker tertinggi pada perempuan, laki-laki, dan anak-anak, dan kesiapan pengembangan registrasi kanker di wilayah lain di Indonesia mengacu pada mod…
Aim: to determine whether serum HER-2/neu level could be used as a prognostic factor in locally advanced breast cancer (LABC) and metastatic breast cancer (MBC). Methods: a prospective cohort study was done in LABC and MBC patients in dr. Sardjito Hospital Yogyakarta from April 2006 to March 2008. Serum concentration of HER-2/neu was measured by ELISA done before and after chemotherapy. HER-…
The prevalence of colorectal cancer has been increasing significantlyover the past20 years is the second leading casuse of cancer related deaths in the united States. Until new, sugical resection remains the only curative treatment for colorectal cancer. Recent studes have suggested that acetyl salicylic acid, is one of the potential chemo preention agent to decrease colorectalcancer prevalence…
Research on the Application of Linear Array HPV genotyping test in detection of HPV genotypes on Cervical Cancer Patients that is intended to study the DNA hybridization method in the identification of genotypes of HPV that cause cervical cancer using diagnostic device Linear Array HPV genotyping test. The aim of this study are to determine and detect the presence of HPV genotypes on sample. T…
Vascular Endothelial Growth Factor (VEGF) adalah protein angiogenik yang dihasilkan oleh sel tumor, dibantu sel endotel dalam peranannya bagi pertumbuhan tumor. VEGF berkaitan dengan vascular endothelial growth factor receptor (VEGF) dipicu keadaan hipoksia dan onkogen ras mutan. VEGF tidak bekerja pada sel endotel istirahat dan pembuluh darah dewsa. Ada 6 betuk isoform VEGF yaitu VEGF-A,B,C,D,…