Bibliografi : hlm. 254-255
Non Steroid Anti-Inflammatory (NSAID) is one type of Anti-Inflammatory drug that is used to treat pain in patients of osteoarthritis (OA) and rheumatoid arthritis (RA). The use of NSAIDs can cause gastrointestinal side effects. To prevent the side effects, NSAIDs are prescribed in combination with gastroprotective agent (GPA). The aim of the study is to determine the factors considered in the G…
Andrographolide, a bioactive component of Andrographis panicuiata (Burm.F) Nees, is the major lactone diterpenoidal bicyclic constituent in this plant which has proven to exert anti-inflammatory activity in vitro which was occurred via several mechanism, e.g inhibition of inducible nitric oxide synthase (iNOS), inhibition of radical oxygen species, and inhibition of NF-kappaB activation, The la…
Three compounds (i.e. benzoylthiourea, 4-nitrobenzoylthiourea, and 4- chlorobenzoylthiourea) have been synthesized from ammonium thiocyanate, substituted benzoyl chlorides, and ammonia as starting materials. The structures of sythesized compounds were confirmed by means of ultra-violet, infrared, magnetic resonance, and mass spectroscopv. All compounds were evaluated for their analgesic and ant…
Inflammation is a physiologic process of body if there is an injury mechanism, but if it's happened excessively can threaten body. Anti-inflammation drugs were needed to control the dangerous effects. Because of synthetic anti-inflammation drugs are known have many harmful side effects, the traditional ones need to develop as altemative, one of them is soybean that guessed have the quality as a…
Quercetin is a flavonoid having anti-inflammatory activity by cyclooxygenase -2 inhibition. In addition quercetin has a cytoprotective activity against gastric ulcer due to its antioxidative activity. The objevtive of this research was to obtain quercetin derivative through selective acetylation and to find out the anti-inflammatory activity and gastric ulcer side effect of the synthesis produc…