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The Effect of Anthelmintics on the Development of Ascaris lumbricoides Eggs (Pengaruh Beberapa Antelmintik terhadap Perkembangan Telur Ascaris lumbricoides)

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The effect of anthelmintics on the development of A. lumbricoides eggs was observed by treating 4 groups of primary school children in North Jakarta. Each group was treated with one of the following anthelmintic i.e. pyrantel pamoate, oxantelk pyrantel pamoate, albendazole and mebendazole. Two weeks after treatment stools positive with A. lumbricoides eggs were cultured in 2 percent potassium bichromate solution for 3 weeks. Among the A. lumbricoides eggs 30.92 percent developed into infective stages after pyrantel pamoate treatment, and 7.21percent after axantel pyrantel pamoate treatment. In the albendazole group among 88 A. lumbricoides eggs not a single one developed into the infective stage. A. lumbricoides eggs were not discovered in the stool cultured obtained from mebendazole groups, which was due to the high cure rate and eggs reduction rate of the drug. It was concluded that no development of A. lumbricoides eggs occured in 3 weeks cultures after albendazole treatment. On the other hand development of A. lumbrioides eggs occured in 3 weeks cultures after albendazole treatment. On the other hand development of A. lumbricoides eggs into infective stage was observed among the oxantel pyrantel pamoate and pyrantel pamoate group. The development of eggs in the oxantel pyrantel pamoate group was slower than the development of eggs in the pyrantel pamoate group.

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Majalah Kedokteran Indonesia,46(11)1996:605-609

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: ., 1996

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ascaris
anthelmintics

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