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Diagnostic Criteria and Management of Diabeticum Dislipidemia (Dislipidemia Diabetik Kriteria Diagnostik dan Penatalaksanaan)

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As estimated that about 50 percent of all population, weither IDDM or NIDDM are dyslipidemid. In NIDDM patients, the most screening-total cholesterol, triglyseride, HDL-cholesterol and calculated LDL-cholesterol should be performed routinely to all diabetic patients. Desirable lipid levels are, total cholesterol less than 200 mg percent, LDL-cholesterol less than 130 mg percent, triglyserides less than 150 percent and HDL-cholesterol more than 45 mg percent in men and more than 55 mg percent in women. The first line measure for managing diabetic dyslipidemia are diet, regular exercises and succesful glycemic control. Patients who do not respond appropriately to non-pharmacologic i.e bile acid sequestrants, nicotinic acid, probucol, fibric acid derivatives and HMG CoA reductase inhibitors. For patients with hypertriglyceridemia and low HDL-cholesterol, fibric acid derivative is recommended. Those with isolated LDL-cholesterol elevation, HMG CoA redutase inhibitors is preferable. For combined elevations in LDL-cholesterol and triglycerides, a fibric acid derivatives such as gemfibrozil and bezafibrate or HMG CoA reductase inhibitors may be chosen, depend on whether the most severe lipid abnormality is an elevated of LDL-cholesterol or triglycerides.

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Majalah Kedokteran Indonesia,45(3)1995:200-205

Publisher

: ., 1995

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Subject(s)

diabetes mellitus

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