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Cervical Glandular Lesion : Frequency and Diagnostic Agreement (Lesi Glandular Serviks : Kekerapan dan Kesepakatan Diagnostik)

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This study has an intention to describe the cervical glandular lesions findings especially the adenocarcinoma insitu (AIS) on cytology and colposcopy and warns the clinicians about the danger of failure in diagnosing the AIS. This study is prospective, and Kappa value was used to describe the agreement of diagnosis. This study was held in authors private colposcopy clinic and Dr. Cipto Mangunkusumo Hospital for over 5 years. AIS was found in 3 cases (0.32 percent) and 2 adenocarcinomas were also found from 932 colposcopic examination series. The first cytology examination and colposcopy failed to diagnose 66.7 percent AIS and 50 percent adenocarcinomas. Agreement between cytology and histology in diagnosing endocervical changes served Kappa value of 0.46, and colposcopy to histology served a better Kappa value (0.67). Glandular involvement findings in high grade squamous intraepithelial lesion (CIN 3) cases on cytology were very low (less than 50 percent) and agreement between first cytology examination and its review was moderate (Kappa 0.43). Conclusion : Routine Pap test using cyrobrush and spatulas should find the cervical glandular lesions, and colposcopic examination could only find the glandular lesion if it was in the squamocolumnar function areas.

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Majalah Kedokteran Indonesia,45(2)1995:120-123

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: ., 1995

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cervix neoplasms

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