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Renoprotective Effects of ACE Inhibitors in the Progression of Diabetic Kidney Disease (Pengaruh Renoprotektif Inhibitor Angiotensin Converting Enzyme (ACE) pada Progresivitas Penyakit Ginjal Diabetik)

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Functional and structural abnormalities in diabetic kidney disease lead to intraglomerular hypertension and albuminuria. Systemic hypertension and genetically inherited defect on autoregulation in preglomerular arterioles will enhance kidney injury in those patients. ACE inhibitors could reduce albuminuria in patients with diabetic nephropathy and animal models. Hemodynamic improvement manifested by the reduction of albuminuria by ACE inhibitors is only seen in the experimental studies. However, recent studies have shown that ACE inhibitors, especially captopril, could give protective effects on kidneys in insulin-dependent diabetics with nephropathy. Captopril also reduces the risk of death, dialysis, and kidney transplantation in those patients.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

Berkala Ilmu Kedokteran,27(1)1995:47-52

Penerbit

: ., 1995

Deskripsi Fisik

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Bahasa

ISBN/ISSN

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Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

glycosuria, renal

Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

Lampiran Berkas

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