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The Effectivity of Jatropha gossypifolia L, J.curcas and Riccinus communis Seeds Extract Against the Schistosomiasis Intermediate Snail, Oncomelania hupensis lindoensis

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At present, Scistosomiasis are still endemic in Indonesia, especially in Napu Highland, Poso Regency, Central Sulawesi Province. Oncomelania hupensis lindoensis,the intermediate host of Scistosomiasis are wide spread in Napu Highland. One effort of snail control on Scistosomiasis control program was used Bayluscide molluscicide every six mounths. Used ofchemical molluscicide have inadequacy because poluted the environtment. Used of herbal molluscicide to be alternative snails control have done. Euphorbiaceae family know have molluscicide activity.

The study aimed to determined the effectiveness of Jatropha gossypiifolia, J. Curcas and Riccinus communis extract and fraction againts O.h Indoensis. The testwas conducted from March-September 2009 in Laboratory of Scistosomiasis Napu. The snails exposed with the solution of Jatropha gossypiifolia, J. Curcas and Riccinus communis extract for 24 hours, the mortality of snails were counted andanalyzed using probit to determine the LC 50 and LC 95 value.

The result showed the methanol extract from Jatrophagossypiifolia, J. Curcas and Riccinus communis have lethal capacity againts O.h Indoensis. The concentration of J.Gossypiifolia seeds extract showed a highest lethal capacity to the snail, with LC 50 value in 10,41 ppm and LC 95 in 18,6ppm. The methanol fraction of J. Gossypiifolia seeds extract was the most effective among the ethyl-acetate fraction and hexanefraction of J. Gossypiifolia seeds extract. Jatropha gossypiifolia may become an alternative to control O.h .lindoensis.

Key words: schistosomiasis, J. gossypifolia, J. curcas, R. communis, O.h. lindoensis

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Series Title

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Call Number

Balaba, 10 (1) 2014 : 9-14

Publisher

Banjarnegara : Loka Litbang P2B2 Banjarnegara., 2014

Collation

6p

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ISBN/ISSN

1858-0882

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Subject(s)

SCHISTOSOMIASIS

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