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Pengaruh Suplementasi Mikroalga Spirulina terhadap Asupan Iodium pada Wanita Usia Subur di Daerah Endemik GAKI
Iodine is an essential micronutrient for thyroid hormone function. The government has implemented mandatory salt iodization to control iodine deficiency disorder (IDD). Spirulina is a microalgae contaiing 94,5μg/g iodine (60 percent RDI of iodine in adult woman), which can be used as alternative source of natural iodine. The purpose of this study was to determine the effect of spirulina supplementation on iodine intake in women of childbearing age in the IDD endemic area.
The design of the study was Randomized Control Trial (RCT) double-blind. The subjects were 60 women of childbearing aged 18-40 years in Kulo Progo, Yogyakarta. Subjects were divided into 2 groups randomly, the treatment group was given spirulina 1 gr/day and the control group was given pacebo, for 3 months. Median Urinary Iodine Excretion (UIE) was used to measure iodine intake.
The result showed that median UIE in both groups at weeks 0 and 6 were sufficient (100-199 μg/L). At week 12 the median UIE in the treatment group were increase to 211 μg/L. There was a significant difference in median UIE at week 12 between 2 groups (P
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