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Gambaran Histopatologi Ginjal Rattus norvegicus Infektif Leptospira (Histopathology of Rattusattus norvegicus Kidney Infected by Leptospira)
A study on the histological structure of Rattus norvegicus kidney infected by Leptospira has been conducted. The purpose of this study was to determine the change of kidney tissue structure of R. norvegicus due to the patogenicity of Leptospira bacteria.
The study was done in Miroto, Central Semarang District, Semarang Municipality. Rattus norvegicus was caught with live trap. The blood and kidney specimen were taken from all the caught rat. Then the blood was serologically examined by using Leptotek Dri-Dot, whereas the kidney was histopatologically observed under the microscope by using Hematoxylin-Eosin staining. The data were collected qualitatively and then analyzed descriptively by describing histological kidney appearance of R. norvegicus which were infected by Leptospira.
The results of this research showed that 11 individuals of R. norvegicus caught and 8 induvidual infected by Leptospira. The results of R. norvegicus histological kidney examination which were infected by Leptospira show capillaries dilatation and hyalinization in glomerulus.
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