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Toksisitas Akut dan Subkronis Ramuan Ekstrak Kelor dan Klabet sebagai Pelancar ASI dan Penambah Gizi

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Insufficient breast milk intake from a mother to their babies may cause a poor infant growth. We have conducted a research on mixture of klabet seed extracts (Trigonella foenum-graecum L.) and kelor leaf extract (Moringa oleifera Lamk.) (1:1) for increasing breast milk production in nursing mothers and nutritional supplement for infants.

The study is a completely randomized design. We used white rats (Rattus novergicus), Wistar strain, as many as 50, that were divided into 5 dose groups for the acute toxicity testing and 40 rats in 4 dose groups for the sub-chronic toxicity testing.The acute toxicity testing of fenugreek seed extracts and moringa leaf extracts (1:1) results in a pseudo value LD50 >4,000 mg/200g bw, therefore we classified the materials to practically non-toxic (PNT). For the subchronic toxicity testing, the result showed a normal state on liver and kidney function.

Keywords : Breast milk; Extract klabet (Trigonella foenum-graecum); Extract kelor (Moringa oleifera); Acute and subchronic toxicity

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Series Title

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Call Number

Jurnal Kefarmasian Indonesia, 4 (2) : 51-64

Publisher

Jakarta : Pusat Biomedis dan Teknologi Dasar Kesehatan., 2014

Collation

14p

Language

ISBN/ISSN

2085-675

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Edition

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Subject(s)

plant extracts
milk, human
BREASTFEEDING

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