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Pengujian Aktivitas Antiacne Nanopartikel Kitosan – Ekstrak Kulit Buah Manggis (Garcinia mangostana)
The antiacne activity of paste and powder of chitosan – Garcinia mangostana extract nanoparticles were observed that it’s against of Propionibacterium acnes. The paste of nanoparticles has been prepared by ionic gelation reaction by mixture 0.2% chitosan solution in acetic acid with Garcinia mangostana 70% ethanol extract and it’s continued by reaction process with 0.1% sodium tripolyphosphate. Meanwhile the powder of nanoparticles was produced by freeze drying process of a paste of the nanoparticles.
The results of antiacne activity of paste and powder of nanoparticles were showed that it’s could against Propionibacterium acnes with the lowest concentration about 0.15%.
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