Typhonium flagelliforme decreases protein expression in murine breast cancer (Typhonium flagelliforme menurunkan ekspresi protein pada kanker payudara mencit) | Perpustakaan Badan Kebijakan Pembangunan Kesehatan

Search by :

ALL Author Subject ISBN/ISSN Advanced Search

Last search:

Text

Typhonium flagelliforme decreases protein expression in murine breast cancer (Typhonium flagelliforme menurunkan ekspresi protein pada kanker payudara mencit)

hodidjah - Personal Name; Taufiqurrahman Nasihun - Personal Name; ; Eni Widayati - Personal Name; Edijanti Goenarwo. - Personal Name;

ABSTRACT
An in vitro experimental research was conducted between October 2013 and January 2014. Neem lea were extracted in ethanol or hexane at various concentrations. A macrodilution test with 48-hour incubation time was done in triplicate on 8 groups of samples. These comprised the neem leaf ethanol extract (NLEE) at 0.5, 1.0, and 2.0 g/dL, neem leaf hexane extract (NLHE) at 0.5, 1.0, and 2.0 g/dL, positive control, and negative control groups. Fungal growth was detected on Sabouroud dextr
BACKGROUND

Aspergillus flavus is one of the causes of aspergillosis, with a high virulence and resistance to standard antifungals, resulting in a high mortality rate. Medicinal plants are increasingly used as they are relatively safer with minimal side effects. Previously we found that the ethanol extract of neem (tadirachia indica A Jus) leaves inhibits 4.flovits growth in vitro. However, most chemical compounds with antifungal effect are nonpolar. The purpose of this research was to compare the antifungal effect of neem leaves extracted in a nonpolar solvent to that of leaves extracted in a polar solvent.

METHODS
ose agar. Statistical analysis use Chi square and Fisher's exact test.

RESULTS
NLHE had a higher, but statistically non-significant, inhibitory effect on A. ems than NLEE (v0.996). At higher concentrations, the antifungal effect of NLHE is better than that of NLEE.

CONCLUSION
There is no significant difference in in-vitro inhibitory effectivity on A. Awns of neem leaves between extracts in polar and nonpolar solvents.

Keywords : Azadiracina indica, neem, A. Plus, ethanol, hexane. Antiftmeal

Availability

Location name is not set UNIVERSITAS MEDICINA, 33 (3) 2014 : 163-170

A0004487

Available

Detail Information

Series Title: -
Call Number: UNIVERSITAS MEDICINA, 33 (3) 2014 : 163-170
Publisher: Jakarta : UNIVERSA MEDICINA/FK UNIVERSITAS TRISAKTI., 2014
Collation: 8p
Language
ISBN/ISSN: 1907-3062
Classification: -
Content Type: -
Media Type: -
Carrier Type: -
Edition: -
Subject(s): -
Specific Detail Info: -
Statement of Responsibility: -

Other version/related

No other version available

File Attachment

No Data

Comments

You must be logged in to post a comment