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Dampak Intervensi Sumber Iodium Alami Spirulina Sp Terhadap Kadar T4 Bebas (FT4) dan Tiroglobulin (TG) Pada Wanita Usia Subur di Daerah Kalibawang Kulon Progo (The Intervention Effect of Spirulina sp as Natural Iodine Source to Free T4 Level and Thyroglobulin Concentration at Women of Child Bearing Age in Kalibawang Kulon Progo)

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ABSRACT

Iodine Deficiency Disorder (1DD) is still a public health problem in Indonesia. Salt iodization was one of OD prevention programme to prevent IDD, however the national coverage for iodized salt is still ess than 90%. Alternative solution to solve IDD elimination is needed to find a better iodine sources. One of nutrient rich source from the sea that was developed to improve the nutritional status is Spirulina sp. Spirulina has high bioavailability due to the simple structure of the cell wall, so that the nutrients contained iodine will be more easily absorbed by the body. The aim of this research was to describe the effect of Spirulina sp to free T4 and thyroglobulin level in women of child bearing age in Kalibawang Kulon Progo regency. This is an experimental study using double blind randomized control trial (RCT).
Subjects are euthyroid child beating woman (1840 years old), with TSH levels of 3 to 6.2 µlUL. They were divided into 2 groups with subjects in control group were given placebo while the treatment group were given Spirulina sp (1 gr/day) for 3 months. Serum for free T4 and thyroglobulin was analysed using ELISA.

The results showed that there were significant changes in free T4 level in both groups after intervention (P 0.05) in thyroglobulin. The intervention using Spirulina sp has potential effect to increase free T4 level, however it did not effect thyroglobulin level.

Keywords: FreeT4, RCT, Spirulina sp, Thyroglobulin

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

MEDIA GIZI MIKRO INDONESIA, 5 (2) 2014 :85-96

Penerbit

Magelang : Media Gizi Mikro Indonesia BP2GAKI., 2014

Deskripsi Fisik

12 p

Bahasa

ISBN/ISSN

2086-5198

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Tipe Media

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